hrp0095p1-563 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Transient multiple pituitary hormone deficiency in critically ill pediatric patients

Dror Nitzan , Adam Dganit , Perl Liat , Eliakim Alon

Objective: Hospitalization in pediatric intensive care unit due to critical illness may be life threatening condition associated with severe acute physical stress and concomitant hormonal changes. Whether these changes represent an adaptive response or need to be treated is still not known.Methods: Pituitary hormones evaluation in four patients who were hospitalized in pediatric intensive care unit due to different sever...

hrp0082p1-d1-135 | Growth | ESPE2014

The Association Between Adipocytes and Growth is Mediated by Growth and Differentiation Factor 5

Shtaif Biana , Dror Nitzan , Bar-Maisels Meytal , Phillip Moshe , Gat-Yablonski Galia

Background: The association between nutrition and growth is common knowledge but the mechanism is still unelucidated. Several reported cases in the literature describe growth without GH, that in most cases were associated with obesity, suggesting, that the adipocytes might have a role in regulating linear growth.Objective and hypotheses: The aim of the study was to search for a skeletal growth factor that is secreted by adipocytes....